Purpura trombocitopenica autoinmune caso clinico y revision bibliografica luis angel sequeira rojas s u m m a r y the itp is a blood illness, characterize by thrombocytopenic, and it variability intense level. Thrombotic thrombocytopenic purpura ttp is the most extensive and dangerous intravascular platelet clumping disorder. Assessment of uk practice for management of acute childhood idiopathic thrombocytopenic purpura against. Moschcowitz was the first to inform multiple hyaline thrombi as the primordial finding of a partial autopsy case. He proposed that a powerful poison with both agglutina. For more than a halfcentury after its initial recognition, mortality was near 100% and the etiology totally obscure. Immunologic thrombocytopenic purpura itp, bone marrow aspirate. Eperto e bases del diagstico e hematologa 4 purpura trombotica trombocitopenica y sindrome hemolitico uremico figura 1. Purpura results from the extravasation of blood cells into the skin andor mucous membranes giving rise to small purple coloured areas that do not disappear under pressure. Purpura trombocitopenica, plaquetas, purpura, autoanticuerpos.
Protocolo clinico e diretrizes terapeuticas purpura. The etiopathogenic mechanisms may result from abnormalities in any of the three components of hemostasis. It can produced in health people, but in children has been associated to viral infection, or bacterial infection. Purpura are injuries caused by the extravasation of blood cells into the skin and or mucous membranes due to hemostasis disorders. Hematologia y oncologia pediatricas ha actualizado sus. Thrombocytopenic purpura is mostly responsible for episodes of mucocutaneous bleeding.
Primary immune thrombocytopenia itp is an acquired immunemediated disorder characterized by isolated low platelet count and the absence of any other cause of the thrombocytopenia. Chronic immune thrombocytopenic purpura itp is a bleeding disorder characterized by increased destruction of platelets due to the production of antiplatelet autoantibodies. Protocolo clinico e diretrizes terapeuticas portaria sasms n. Approach to the investigation and management of immune thrombocytopenic purpura in children.
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